The University of Michigan- Shanghai Jiao Tong University Joint Institute (UM-SJTU JI) stands at the forefront of technological innovation with its unique academic atmosphere and advanced scientific explore. JI boasts a strong research team which keeps innovating and strives to produce results that will lead the industry and ultimately benefit the human beings.
In order to help the public discover the mystery of scientific research, JI has launched a series of mini-workshop to introduce its faculty’s research.
Clinical applications of photoacoustic endoscopy (Courtesy of New England Journal of Medicine 2017)
The past decade has seen tremendous progress in photoacoustic (PA) imaging. PA imaging uniquely combines high optical contrast and low acoustic scattering. As an emerging hybrid imaging modality, it has found wide biomedical applications, including imaging of microcirculation, atherosclerotic vulnerable plaque identification, and endoscopic imaging.
At his seminar titled “Photoacoustic Imaging: Algorithms and Probes,” Professor Sung-Liang Chen presented his research team’s recent progress on miniature photoacoustic probes and some photoacoustic imaging algorithms. He introduced the synthetic aperture focusing technique(SAFT) based on mirror scan, discussed the deconvolution for acoustic-resolution PA microscopy (AR-PAM), and demonstrated SAFT combined with deconvolution for three-dimensional AR-PAM.
(a) Schematic of the miniature photoacoustic probe.
(b) An arrangement of laser illumination. Length unit: mm.
(c) Photograph of the imaging
In vivo photoacoustic imaging of blood vessels in a mouse’s ear.
Professor Chen’s research team has made many achievements in the theory and manufacturing of miniature photoacoustic probes. The team has presented and produced a photoacoustic endoscopic probe based on synthetic focused aperture technology, a miniature photoacoustic-ultrasound dual-mode imaging probe for high-resolution photoacoustic / ultrasound imaging, and a photoacoustic camera capable of acquiring high-quality live photoacoustic imaging. At the same time, they have also developed miniature optical-resolution photoacoustic microscopy probes for in-vivo imaging and all-optical high-intensity focused ultrasound probes that have great potential for precision therapeutic applications.
Professor Sung-Liang Chen is currently an assistant professor at the University of Michigan-Shanghai Jiao Tong University Joint Institute. He received his doctoral degree in electrical engineering at the University of Michigan, Ann Arbor, and postdoctoral training at the University of Michigan Medical School. He has published 27 papers in SCI journals such as “Nature Photonics,” “Optics Letters,” and “Optics Express,” which have been cited 807 times. His research results of the photoacoustic terahertz detection have been reported by mainstream scientific media such as “Gizmag Emerging Technology Magazine,” “IEEE Spectrum,” “Michigan News,” “R & D Magazine,” “Radiology Daily,” and “Science Daily.” His research interests include optical ultrasound sensors, optical imaging systems, and biomedical photoacoustic imaging.
